Endocrine Abstracts

Non-neoplastic pituitary stalk thickening is rare in patients without infiltrative disorders and diabetes insipidus. We present a non-diabetic patient with end stage renal failure with hyperprolactinaemia and pituitary stalk thickening.A 53-year-old Nigerian gentleman presented with reduced libido, erectile dysfunction and painful gynaecomastia. He denied galactorrhea, headaches or visual disturbances. He previously received spironolactone for resistant ...

We report a case of a 57-year-old woman with profound uncontrolled hypothyroidism diagnosed in 1999. At her first Endocrine clinic visit in 2015, her TSH level was 93.4 mU/l with FT4 level of 4.8 pmo/l. Despite increasing her Levothyroxine dose, her TSH level remained persistently above 80 mU/l with a low FT4. She had a gastroscopy and coeliac screening which were non-significant. Triiodothyronine 10 mg was added to Levothyroxine 100 mg once daily in October 2015. However, she...

Aim: This is a retrospective study of imaging with adrenal incidentalomas at our DGH to assess clinical practice. Their management was followed and compared with the European Society of Endocrinology (ESE) Clinical Practice Guidelines 2016 for management of adrenal incidentalomas. The aim was to improve clinical service by developing a local management pathway.Materials and Methods: Data was collected for two years from 2018 to 2019 which included all im...

Primary Hyperparathyroidism (pHPT) affects approximately 1:2000 women under 40 years of age, so pHPT in pregnancy is uncommon. It is associated with significantly increased risks of morbidity for mother and foetus. Conventionally, surgery is recommended, ideally early in the second trimester. A 31-year-old woman attended the Accident and Emergency department at 26+4 weeks of her third gestation, with severe loin pain and fever. She had a past medical history of pyelonephritis....

Generously supported by IPSEN)-->Moderate hyperprolactinaemia (<1000 mU/l) is a common abnormal biochemical finding in patients with end-stage renal failure (ESRF). The underlying pathophysiological mechanism is thought to be due to a combination of increased prolactin secretion as well as delayed renal clearance. There are no current clear guidelines for the treatment of ESRF-induced symptomatic hyperprolactinaemia but renal tra...

Case history: We describe a rare case of a 59-year-old woman, whose hypercortisolism was unmasked following transphenoidal surgery for Acromegaly. She presented to the Endocrine Clinic in 2006 with acromegalic features and MRI revealing a pituitary macroadenoma 20×18×18 mm. Repeat dynamic evaluation showed inadequate GH suppression (initially normal), raising the possibility of early rumbling Acromegaly. 0900 h serum cortisol was 287 nmol/l. She was started on Caberg...

Coexistence of Acromegaly with Cushing’s syndrome in the same individual is rare. We herein describe a case of a 59-year-old woman, whose hypercortisolism was unmasked following transphenoidal surgery for Acromegaly.She presented to the Endocrine Clinic in 2006 with acromegalic features and MRI revealing a pituitary macroadenoma 20×18×18 mm. Repeat dynamic evaluation showed inadequate GH suppression (initially normal), raising the possibil...